The first Advances in Sleep and Circadian Science (ASCS) meeting took place at the Sheraton Sand Key Resort, in Clearwater Beach, Florida from February 1st-4th, 2019. The meeting was developed and sponsored by the Sleep Research Society (SRS) to highlight and catalyze integrative sleep and circadian science. Over three days and eight sessions, the speakers and discussants skillfully weaved together the parallel threads of sleep and circadian rhythms research by not only presenting their own data but presenting their views on the avenues of concordance between the two fields in their own research outlook. Three plenary sessions included a lecture from Dr. Michael Rosbash, 2017 Nobel Laureate and TED style talks by Drs. Chiara Cirelli, Charles Czeisler, Joe Takahashi, and Dan Buysse, discussing the Future of Transdisciplinary Sleep and Circadian Science. The meeting was attended by 174 sleep and circadian scientists from around the world.